The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Mar. 21, 2016
Applicants:

International Aids Vaccine Initiative, New York, NY (US);

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

Shailendra Kumar Sharma, La Jolla, CA (US);

Richard Wyatt, La Jolla, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); C07K 16/10 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/55577 (2013.01); A61K 2039/572 (2013.01); A61K 2039/575 (2013.01); A61K 2039/645 (2013.01); C07K 14/005 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16171 (2013.01);
Abstract

The present application relates to novel HIV-1 envelope glycoproteins which may be utilized as an HIV-1 vaccine immunogens, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.


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