The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Sep. 03, 2014
Applicant:

Kyoto University, Kyoto, JP;

Inventors:

Akira Kakizuka, Takatsuki, JP;

Ken Ebihara, Shimotsuke, JP;

Megumi Abe, Kyoto, JP;

Chihiro Ebihara, Shimotsuke, JP;

Assignee:

Kyoto University, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); C07D 213/76 (2006.01); C07D 409/04 (2006.01); A61K 45/06 (2006.01); C07C 245/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/655 (2013.01); A61K 45/06 (2013.01); C07C 245/10 (2013.01); C07D 213/76 (2013.01); C07D 409/04 (2013.01);
Abstract

The present invention provides a compound of formula (I) which improves leptin resistance, a pharmaceutical composition comprising the compound, a method for manufacturing a pharmaceutical for improving leptin resistance comprising using the compound, use of the compound for manufacturing a pharmaceutical for improving leptin resistance, and a method for improving leptin resistance comprising administering the compound or the pharmaceutical composition. The improvement of leptin resistance can lead treatment and/or prevention of a disorder associated with leptin resistance, including, particularly, metabolic disorder, obesity, hyperphagia, steatosis, diabetes, and dyslipidemia.


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