The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Sep. 08, 2015
Applicant:

Integral Biosystems Llc, Bedford, MA (US);

Inventors:

Shikha P. Barman, Bedford, MA (US);

Moli Liu, Lowell, MA (US);

Koushik Barman, Bedford, MA (US);

Kevin L. Ward, Arlington, MA (US);

Brendan Hackett, Somerville, MA (US);

Assignee:

Integral Biosystems LLC, Bedford, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 31/56 (2006.01); A61K 31/5575 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61K 9/7007 (2013.01); A61K 9/0051 (2013.01); A61K 31/5575 (2013.01); A61K 31/56 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01);
Abstract

A nanostructured biocompatible wafer for placement in the conjunctival cul-de-sac. The wafer contains a tissue-reactive mucoadhesive polymer and a mesh formed of a plurality of hydrophobic polymer fibers. Also provided is a method for treating glaucoma, an ocular surface disorder, or an ocular surface infection using the nanostructured biocompatible wafer. Additionally, an injectable sustained-release formulation for treating an ocular disorder is disclosed. The formulation includes a drug contained within a plurality of microparticles formed of a biodegradable polymer and are coated with a tissue-reactive compound. Further provided is a method for treating an ocular disorder by injecting the microparticulate sustained release formulation.


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