The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Oct. 26, 2012
Applicant:

Beckman Coulter, Inc., Brea, CA (US);

Inventors:

Brian D. Peterson, Ontario, CA (US);

Dale Alan Owens, Corona, CA (US);

Peter S. Kotowski, Yorba Linda, CA (US);

Sunil S. Deliwala, Placentia, CA (US);

Craig A. Hudson, Brownsburg, IN (US);

James H. Reyes, Victoville, CA (US);

Clive Cheung, Norco, CA (US);

Tom Tran, Irvine, CA (US);

Anna X. Lou, Arcadia, CA (US);

Jane Luo, Irvine, CA (US);

Jean-Marc Rene Lucien Busnel, Marseille, FR;

Chitra K. Ratnayake, Yorba Linda, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); G01N 30/72 (2006.01); H01J 49/02 (2006.01); H01J 49/16 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44743 (2013.01); G01N 27/44717 (2013.01); G01N 30/7266 (2013.01); H01J 49/022 (2013.01); H01J 49/165 (2013.01); Y10T 307/313 (2015.04);
Abstract

Aspects of the innovations presented herein relate to improved systems that in some embodiments perform capillary electrophoresis (CE) and CE in conjunction with electrospray ionization (ESI) as an input to a mass spectrometry system (MS). Some embodiments use a high voltage isolated CE power supply that is configured to float on the high voltage output of an ESI-MS power supply, with a protective resistance in the ESI-MS path, as well as DC/DC converter isolation and communication system isolation for the isolated CE power supply. Some embodiments additionally use a cartridge assembly integrating separation and conductive fluid capillaries with fluid cooling and protective retractable housings for the capillary end portions and for the ESI output. The protective housing may further be used with an adapter for interfacing with different MS systems.


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