The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Jul. 01, 2015
Applicants:

André A. Adams, Burke, VA (US);

Michael Daniele, Arlington, VA (US);

Frances S. Ligler, Fuquay Varina, NC (US);

Inventors:

André A. Adams, Burke, VA (US);

Michael Daniele, Arlington, VA (US);

Frances S. Ligler, Fuquay Varina, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); B29D 99/00 (2010.01); B01J 19/00 (2006.01); B01L 3/00 (2006.01); G02B 6/032 (2006.01); C12M 3/00 (2006.01); C12M 1/12 (2006.01); B29L 9/00 (2006.01); B29L 23/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); B01J 19/0093 (2013.01); B01L 3/502707 (2013.01); B29D 99/0078 (2013.01); C12M 21/08 (2013.01); C12M 25/10 (2013.01); C12M 25/12 (2013.01); C12M 25/14 (2013.01); C12N 5/0602 (2013.01); G02B 6/032 (2013.01); A61F 2240/001 (2013.01); B01J 2219/0086 (2013.01); B01J 2219/0093 (2013.01); B01J 2219/00783 (2013.01); B01J 2219/00831 (2013.01); B01J 2219/00833 (2013.01); B01J 2219/00873 (2013.01); B01J 2219/00889 (2013.01); B01J 2219/00891 (2013.01); B01J 2219/00936 (2013.01); B01L 3/502746 (2013.01); B01L 3/502776 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/10 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/12 (2013.01); B01L 2300/16 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/084 (2013.01); B29K 2995/006 (2013.01); B29K 2995/0056 (2013.01); B29L 2009/00 (2013.01); B29L 2023/00 (2013.01); G02B 2006/0325 (2013.01);
Abstract

A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.


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