The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Nov. 05, 2012
Applicant:

Argen-x N.v., Breda, NL;

Inventors:

Johannes Joseph Wilhelmus De Haard, Breda, NL;

Natalie De Jonge, Breda, NL;

Anna Hultberg, Breda, NL;

Christophe Blanchetot, Destelbergen, BE;

Karen Silence, Breda, NL;

Peter Ulrichts, Breda, NL;

Torsten Dreier, Breda, NL;

Assignee:

ARGEN-X N.V., Breda, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 19/00 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/00 (2013.01); C07K 14/435 (2013.01); C07K 14/70575 (2013.01); C07K 14/715 (2013.01); C07K 16/00 (2013.01); C07K 16/2863 (2013.01); C07K 16/2875 (2013.01); C07K 19/00 (2013.01); G01N 33/6854 (2013.01); C07K 2317/14 (2013.01); C07K 2317/22 (2013.01); C07K 2317/34 (2013.01); C07K 2319/40 (2013.01);
Abstract

Provided are chimeric, camelid-human (e.g., llama-human) polypeptides comprising a first antigenic polypeptide portion and a second antigenic polypeptide portion wherein the first antigenic portion is a derived from a first portion of a camelid (e.g., llama) and the second antigenic portion is a human polypeptide homolog of a second portion of the camedid antigen. The chimeric polypeptides are useful inter alia for epitope mapping and generation of antibodies that bind to a desired region of human antigen.


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