The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Sep. 24, 2014
Applicant:

University of Ulsan Foundation for Industry Cooperation, Ulsan, KR;

Inventors:

Han Choe, Seoul, KR;

Han Bong Ryu, Seoul, KR;

Bich Hang Do, Hochiminh, VN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/535 (2006.01); C07K 2/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/535 (2013.01); C07K 2/00 (2013.01); C07K 2319/21 (2013.01);
Abstract

The present invention relates to a water-soluble expression and a purification method of a human granulocyte colony-stimulating factor (hGCSF) recombinant protein having biological activities using an N-terminal tag, and provides a recombinant expression vector containing a solubility enhancing tag and a hGCSF gene. In addition, provided are: a recombinant microorganism transformed with the recombinant expression vector; a method for producing a hGCSF recombinant protein (rhGCSF); and a rhGCSF produced by the production method.


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