The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Oct. 05, 2016
Var2 Pharmaceuticals Aps, Copenhagen N, DK;
Ali Salanti, Bronshoj, DK;
Thor Grundtvig Theander, Greve, DK;
Mads Daugaard, Vancouver, CA;
Morten Nielsen, Birkerod, DK;
Madeleine Dahlback, Swedala, SE;
Thomas Mandel Clausen, Copenhagen K, DK;
VAR2 PHARMACEUTICALS APS, Kobenhavn N, DK;
Abstract
The present invention relates to functional binding fragments comprising the minimal binding fragments of VAR2CSA, to antibodies against such binding fragments of VAR2CSA, nucleic acids encoding such fragments of VAR2CSA as well as methods for their production. The invention further relates to conjugates and fusion proteins of VAR2CSA polypeptides including the minimal binding fragments and their use, in particular in the treatment of conditions associated with expression of chondroitin sulfate A (CSA), such as an inappropriate expression of chondroitin sulfate A (CSA).