The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Aug. 29, 2013
Applicant:
Glaxosmithkline Biologicals SA, Rixensart, BE;
Inventors:
Fabio Bagnoli, Monteriggioni, IT;
Fabiana Falugi, Chicago, IL (US);
Guido Grandi, Segrate, IT;
Massimo Mariani, Siena, IT;
Mikkel Nissum, Casciano di Murlo, IT;
Michele Pallaoro, Siena, IT;
Silvana Savino, Tavarnelle Val di Pesa, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); A61K 39/085 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); A61K 39/085 (2013.01); A61K 2039/55505 (2013.01);
Abstract
Elimination of disulphide bond formation of cysteine-containingantigens enhances antigen stability. The invention provides variant forms of cysteine-containingantigen with a point mutation that replaces, deletes or modifies the cysteine residue.