The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Jul. 13, 2017
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Shingo Yamamoto, Osaka, JP;

Toshio Yoshizawa, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/00 (2006.01); A61K 31/54 (2006.01); C07D 473/34 (2006.01); A61K 31/522 (2006.01);
U.S. Cl.
CPC ...
C07D 473/34 (2013.01); A61K 31/522 (2013.01);
Abstract

Compounds represented by general formula (I) (all of the symbols in the formula conform to the definitions in the Description) are compounds that, in addition to having a Btk-selective inhibitory activity, exhibit an excellent metabolic stability and can avoid hepatotoxicity or the like, and as a consequence can provide safe therapeutic agents for diseases in which B cells or mast cells participate.


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