The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Mar. 10, 2015
Applicants:
Merck Patent Gmbh, Darmstadt, DE;
Cancer Research Technology Limited, London, GB;
Inventors:
Kai Schiemann, Seeheim-Jugenheim, DE;
Frank Stieber, Einhausen, DE;
Michel Calderini, Darmstadt, DE;
Julian Blagg, Surrey, GB;
Aurelie Mallinger, Affleville, FR;
Dennis Waalboer, Ljmuiden, NL;
Christian Rink, Bonn, DE;
Simon Ross Crumpler, Herfordshire, GB;
Assignees:
MERCK PATENT GMBH, Darmstadt, DE;
Cancer Research Technology Limited, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 19/02 (2006.01); A61P 35/00 (2006.01); C07D 471/10 (2006.01); A61K 31/444 (2006.01); A61P 25/16 (2006.01); C07D 401/14 (2006.01); C07D 471/20 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/499 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 417/14 (2006.01); C07D 498/10 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/20 (2013.01); A61K 31/444 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/499 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 417/14 (2013.01); C07D 471/10 (2013.01); C07D 498/10 (2013.01); C07D 519/00 (2013.01);
Abstract
The invention provides novel substituted pyridyl piperidine compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases such as cancer, inflammatory or degenerative diseases.