The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Nov. 18, 2016
Phyton Holdings, Llc, San Antonio, TX (US);
Brian A. Bucher, Boston, MA (US);
Edward M. Desimone, III, Indianapolis, IN (US);
Roland R. Franke, Gloucester, MA (US);
Rex T. Gallagher, Hampton, MA (US);
Barry J. Hand, Acton, MA (US);
Christopher D. Howe, Beverly, MA (US);
James H. Johnson, Edenton, NC (US);
John S. Juchum, Kingston, NH (US);
Marc A. Plante, Middleton, MA (US);
T.G. Sambandam, Uxbridge, MA (US);
Dong S. Yang, Quincy, MA (US);
Phyton Holdings, LLC, San Antonio, TX (US);
Abstract
A method of crystallizing docetaxel is disclosed. The method comprises (a) combining docetaxel and at least one solubilizing solvent to obtain a solution, wherein the solubilizing solvent is selected from the group consisting of acetone, methyl-tert-butyl ether, tetrahydrofuran (THF), and acetonitrile and (b) adding an anti-solvent to the solution to obtain a crystalline docetaxel, wherein the anti-solvent is water.