The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Apr. 26, 2016
Applicant:
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Inventors:
Otto Phanstiel, IV, Oviedo, FL (US);
Aaron Muth, Orlando, FL (US);
Assignee:
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 211/31 (2006.01); A61K 31/137 (2006.01); A61K 31/785 (2006.01); C08G 73/02 (2006.01); A61K 31/138 (2006.01); C07C 211/27 (2006.01); C07C 211/30 (2006.01);
U.S. Cl.
CPC ...
C07C 211/31 (2013.01); A61K 31/137 (2013.01); A61K 31/138 (2013.01); A61K 31/785 (2013.01); C07C 211/27 (2013.01); C07C 211/30 (2013.01); C08G 73/0206 (2013.01);
Abstract
Disclosed herein are di-substituted aryl polyamine compounds and methods of making and using the same. The di-substituted polyamine compounds act as PTS targeting agents, which selectively target the polyamine transport system (PTS) with high efficacy and have improved stability in the presence of amine oxidases.