The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Sep. 29, 2017
Applicant:

Denovo Sciences, Inc., Plymouth, MI (US);

Inventors:

Kalyan Handique, Ann Arbor, MI (US);

Kyle Gleason, Brighton, MI (US);

Austin Payne, Ypsilanti, MI (US);

Priyadarshini Gogoi, Ann Arbor, MI (US);

Saedeh Sepehri Javdani, Ypsilanti, MI (US);

Christopher Siemer, Ypsilanti, MI (US);

Yi Zhou, Plymouth, MI (US);

Assignee:

DeNovo Sciecnes, Inc., Plymouth, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 35/10 (2006.01); G01N 35/00 (2006.01); C12Q 1/68 (2018.01); B01L 7/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502715 (2013.01); B01L 7/52 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6841 (2013.01); G01N 33/56972 (2013.01); G01N 35/0098 (2013.01); G01N 35/1079 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/185 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0683 (2013.01);
Abstract

A system and method for capturing and analyzing cells comprising: a fluid delivery module; a reservoir configured to receive a biological sample including a target cell population and at least one fluid from the fluid delivery module; a manifold configured to receive and distribute the biological sample and at least one fluid from the reservoir into a cell capture device; a waste chamber configured to couple to the manifold; and a pump configured to couple to the waste chamber. In embodiments of the system configured to promote further purification of captured cells, the system can further comprise a magnet that enables further separation of captured cells from undesired sample materials. The system can additionally further comprise a heater configured to heat at least one fluid and/or biological sample, and a cell capture device configured to couple to the manifold, in order to facilitate capture of the target cell population.


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