The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Jul. 23, 2008
Applicants:

Eugen Ermantraut, Jena, DE;

Thomas Kaiser, Hohlstedt, DE;

Torsten Schulz, Jena, DE;

Katrin Steinmetzer, Jena, DE;

Thomas Ullrich, Jena, DE;

Inventors:

Eugen Ermantraut, Jena, DE;

Thomas Kaiser, Hohlstedt, DE;

Torsten Schulz, Jena, DE;

Katrin Steinmetzer, Jena, DE;

Thomas Ullrich, Jena, DE;

Assignee:

CLONDIAG GMBH, Jena, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/68 (2018.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502738 (2013.01); B01L 3/5027 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6848 (2013.01); C12Q 1/703 (2013.01); C12Q 1/708 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/18 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0655 (2013.01);
Abstract

A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative for the presence and/or amount of the target molecules, a microfluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the microfluidic network.


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