The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Mar. 14, 2016
Applicants:

Kabushiki Kaisha Toshiba, Minato-ku, JP;

Toshiba Medical Systems Corporation, Otawara-shi, JP;

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Minoru Nakatsugawa, New York, NY (US);

John Wayne Haller, Vernon Hills, IL (US);

Robert Andrew Davey, Edinburgh, GB;

Rachel-Louise Kvertus Koktava, Edinburgh, GB;

Kosuke Sakaue, Otawara, JP;

Todd McNutt, Baltimore, MD (US);

Harry Quon, Baltimore, MD (US);

Scott Patrick Robertson, Baltimore, MD (US);

Zhi Cheng, Baltimore, MD (US);

Assignees:

KABUSHIKI KAISHA TOSHIBA, Minato-ku, JP;

TOSHIBA MEDICAL SYSTEMS CORPORATION, Otawara-shi, JP;

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/103 (2006.01); G06T 11/00 (2006.01); A61N 5/10 (2006.01); G06T 7/00 (2017.01); A61B 6/06 (2006.01); A61B 6/00 (2006.01); A61B 6/03 (2006.01);
U.S. Cl.
CPC ...
A61N 5/1039 (2013.01); A61B 6/032 (2013.01); A61B 6/06 (2013.01); A61B 6/461 (2013.01); A61B 6/469 (2013.01); A61N 5/1049 (2013.01); A61N 5/1071 (2013.01); G06T 7/0089 (2013.01); G06T 11/008 (2013.01); G06T 2207/10081 (2013.01); G06T 2211/421 (2013.01); G06T 2211/424 (2013.01);
Abstract

An apparatus for determining a contour of a treatment region in a patient includes a computer processor to receive input regarding a contour of at least one organ-at-risk (OAR) adjacent to the treatment region; receive input regarding an initial contour of the treatment region; predict a radiation toxicity to the at least one OAR based on the contour of the at least one OAR, the initial contour of the treatment region, and a radiation treatment regimen; determine whether the predicted radiation toxicity exceeds a threshold; and determine a contour of the treatment region by iteratively modifying the initial contour of the treatment region, and any subsequent modified contours of the treatment region, until a stopping condition is satisfied. The stopping condition can be a preselected number of iterations or that the predicted radiation toxicity using the contour in place of the initial contour is first calculated is below said threshold.


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