The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Jan. 31, 2012
Nanoparticle coated with ligand introduced with long hydrophobic chain and method for preparing same
Jae Min Jeong, Seoul, KR;
Young Kyoung Lee, Seoul, KR;
Dong Soo Lee, Seoul, KR;
June-key Chung, Seoul, KR;
Myung Chul Lee, Seoul, KR;
Jae Min Jeong, Seoul, KR;
Young Kyoung Lee, Seoul, KR;
Dong Soo Lee, Seoul, KR;
June-Key Chung, Seoul, KR;
Myung Chul Lee, Seoul, KR;
CELLBION CO., LTD., Seoul, KR;
Abstract
The present invention relates to a nanoparticle having a linker connected to a long alkane or alkene chain, and a method for preparing the nanoparticle. The alkyl chain of Cintroduced with a ligand of the present invention can be coated on a hydrophobic nanoparticle through a noncovalent bond, enabling easy introduction of various ligands to the nanoparticle, and the nanoparticle having various functional groups prepared using the method can be applied to fluorescent detection, MRI, raman spectroscopy, optical detection, PET, SPECT, or gamma image device, and the ligand of the visualization agents can be modified to be used for new vessels detection, cancer cell detection, immunocyte detection, hepatocyte detection, cell death detection, and gene detection.