The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Oct. 19, 2012
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Tatos Akopian, West Roxbury, MA (US);
Olga Kandror, Newton, MA (US);
Alfred Lewis Goldberg, Brookline, MA (US);
Ravikiran M. Raju, Cambridge, MA (US);
Meera Unnikrishnan, Sienna, IT;
Eric J. Rubin, Waban, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A01N 37/18 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 38/12 (2006.01); A61K 38/16 (2006.01); A61K 38/10 (2006.01); A61P 31/04 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 38/55 (2006.01); A61K 39/04 (2006.01); A61K 38/15 (2006.01); A61K 38/48 (2006.01); C07K 5/08 (2006.01); A61K 45/06 (2006.01); A61K 31/055 (2006.01); A61K 31/70 (2006.01); C12N 15/113 (2010.01); C12Q 1/37 (2006.01); C07K 5/097 (2006.01);
U.S. Cl.
CPC ...
A61K 38/55 (2013.01); A61K 31/055 (2013.01); A61K 31/70 (2013.01); A61K 38/04 (2013.01); A61K 38/12 (2013.01); A61K 38/15 (2013.01); A61K 38/482 (2013.01); A61K 39/04 (2013.01); A61K 45/06 (2013.01); C07K 5/08 (2013.01); C12N 15/1137 (2013.01); C12Q 1/37 (2013.01); C12Y 304/21092 (2013.01); C07K 5/0821 (2013.01); G01N 2500/00 (2013.01);
Abstract
The technology described herein relates to treatments for tuberculosis which target the ClpP1P2 protease complex, including ClpC1. Further embodiments relate to assays and screens for modulators of the ClpP1P2 protease complex, including ClpC1.