The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Mar. 10, 2016
Applicant:
University of Cincinnati, Cincinnati, OH (US);
Inventor:
Daniel J. Hassett, Cincinnati, OH (US);
Assignee:
UNIVERSITY OF CINCINNATI, Cincinatti, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7036 (2006.01); A61K 31/198 (2006.01); A61K 33/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7036 (2013.01); A61K 31/198 (2013.01); A61K 33/00 (2013.01);
Abstract
Compositions and methods of utilizing the same are provided for treating bacterial infections. The compositions comprise acidified nitrite in combination with an iron chelator and an antibiotic. The compositions of the present invention are effective at treating bacterial infections with minimal to no side effects. Surprisingly, the combination of these three agents has a synergistic effect, which advantageously permits a lower dose of one or more of the active agents (e.g., the antibiotic).