The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Oct. 03, 2016
Applicant:
Seattle Children's Hospital, Seattle, WA (US);
Inventors:
Allison A. Eddy, Seattle, WA (US);
Daryl M. Okamura, Shoreline, WA (US);
Assignee:
Seattle Children's Hospital, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/13 (2006.01); A61K 31/145 (2006.01);
U.S. Cl.
CPC ...
A61K 31/145 (2013.01);
Abstract
Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition, interstitial fibroblasts, interstitial volume, expression of Collagen I mRNA and protein, expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment.