The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Nov. 04, 2011
Applicants:

Ryan C. Bailey, Urbana, IL (US);

Abraham J. Qavi, Champaign, IL (US);

Jared T. Kindt, Champaign, IL (US);

Ji-yeon Byeon, Daejeon, KR;

Matthew S. Luchansky, Champaign, IL (US);

Melinda S. Mcclellan, Champaign, IL (US);

Adam L. Washburn, Savoy, IL (US);

Tate Owen, Del Mar, CA (US);

Martin Anthony Gleeson, San Diego, CA (US);

Lawrence C. Gunn, Iii, Encinitas, CA (US);

Inventors:

Ryan C. Bailey, Urbana, IL (US);

Abraham J. Qavi, Champaign, IL (US);

Jared T. Kindt, Champaign, IL (US);

Ji-Yeon Byeon, Daejeon, KR;

Matthew S. Luchansky, Champaign, IL (US);

Melinda S. McClellan, Champaign, IL (US);

Adam L. Washburn, Savoy, IL (US);

Tate Owen, Del Mar, CA (US);

Martin Anthony Gleeson, San Diego, CA (US);

Lawrence C. Gunn, III, Encinitas, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); G01N 21/75 (2006.01); C12Q 1/68 (2018.01); G01N 33/543 (2006.01); G01N 21/77 (2006.01);
U.S. Cl.
CPC ...
G01N 21/75 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6825 (2013.01); G01N 21/7746 (2013.01); G01N 33/54373 (2013.01); G01N 2021/7789 (2013.01);
Abstract

Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.


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