The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Aug. 13, 2014
Applicant:

Novozymes A/s, Bagsvaerd, DK;

Inventors:

Michael Schilling, Berlin, DE;

Christine Lang, Berlin, DE;

Andreas Raab, Berlin, DE;

Assignee:

Novozymes A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 33/00 (2006.01); C07K 14/705 (2006.01); C12P 21/02 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C12P 33/00 (2013.01); C07K 14/705 (2013.01); C12N 15/81 (2013.01); C12P 21/02 (2013.01);
Abstract

The invention relates to an isolated, genetically modified, living non-mammal organism, having increased HMG-CoA-reductase activity compared to the wild type, and having reduced C24-methyltransferase and/or delta22-desaturase activity compared to the wild type. The invention is characterized in that the organism has increased dehydrocholesterol-delta70-reductase activity compared to the wild type. The invention further relates to different uses of such an organism, to a test kit comprising such an organism, and to a membrane extract of such an organism.


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