The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Jun. 30, 2011
Applicants:

Simon Mark Jackson, San Carlos, CA (US);

Nigel Pelham Clinton Walker, Burlingame, CA (US);

Derek Evan Piper, Santa Clara, CA (US);

Bei Shan, Redwood City, CA (US);

Wenyan Shen, Palo Alto, CA (US);

Joyce Chi Yee Chan, San Francisco, CA (US);

Chadwick Terrence King, North Vancouver, CA;

Randal Robert Ketchem, Snohomish, WA (US);

Christopher Mehlin, Seattle, WA (US);

Teresa Arazas Carabeo, Seattle, WA (US);

Qiong Cao, Daly City, CA (US);

Inventors:

Simon Mark Jackson, San Carlos, CA (US);

Nigel Pelham Clinton Walker, Burlingame, CA (US);

Derek Evan Piper, Santa Clara, CA (US);

Bei Shan, Redwood City, CA (US);

Wenyan Shen, Palo Alto, CA (US);

Joyce Chi Yee Chan, San Francisco, CA (US);

Chadwick Terrence King, North Vancouver, CA;

Randal Robert Ketchem, Snohomish, WA (US);

Christopher Mehlin, Seattle, WA (US);

Teresa Arazas Carabeo, Seattle, WA (US);

Qiong Cao, Daly City, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/40 (2006.01); A61K 31/405 (2006.01); A61K 31/44 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61K 31/66 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 31/405 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61K 31/66 (2013.01); A61K 39/395 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C12N 15/1137 (2013.01); A61K 2039/505 (2013.01); C07K 2299/00 (2013.01); C07K 2317/14 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.


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