The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Apr. 29, 2016
Applicants:

The University of Tokyo, Bunkyo-ku, Tokyo, JP;

Chugai Seiyaku Kabushiki Kaisha, Kita-ku, Tokyo, JP;

Inventors:

Hiroyuki Aburatani, Bunkyo-ku, JP;

Shumpei Ishikawa, Bunkyo-ku, JP;

Shigeto Kawai, Meguro-ku, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3061 (2013.01); C07K 16/28 (2013.01); G01N 33/57407 (2013.01); G01N 33/57426 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); G01N 2800/52 (2013.01);
Abstract

Disclosed is a monoclonal antibody binding to an ITM2A protein. This antibody is useful in the diagnosis, prevention, and treatment of cancer such as Ewing's sarcoma, T cell leukemia, T cell lymphoma, acute myeloid leukemia, B cell tumor, and multiple myeloma. The present invention also provides a pharmaceutical composition, a cell growth inhibitor, and an anticancer agent containing the antibody as an active ingredient, and a method for treating cancer, a method for predicting the efficacy of cancer treatment, and a method for determining the presence of cancer in a test subject using the antibody.


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