The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Sep. 24, 2013
Applicant:

Kaneka Corporation, Osaka, JP;

Inventors:

Shinichi Yoshida, Takasago, JP;

Dai Murata, Takasago, JP;

Fuminori Konoike, Takasago, JP;

Keita Iguchi, Takasago, JP;

Tomoyuki Nakaishi, Takasago, JP;

Masahiro Hayashi, Takasago, JP;

Assignee:

KANEKA CORPORATION, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/38 (2006.01); B01J 20/26 (2006.01); C07K 1/22 (2006.01); C07K 14/31 (2006.01); C07K 16/06 (2006.01); C07K 17/00 (2006.01); C07K 16/00 (2006.01); C07K 16/12 (2006.01); C07K 17/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); B01D 15/3809 (2013.01); C07K 1/22 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); C07K 16/1271 (2013.01); C07K 17/00 (2013.01); C07K 17/12 (2013.01); B01J 2220/4856 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01); C07K 2317/92 (2013.01);
Abstract

An object of the present invention is to develop techniques to create novel engineered protein ligands that maximize the binding capacity and binding efficiency to a target molecule of affinity separation matrices on which the protein ligands are immobilized. The present invention provides protein ligands (variants) that can be immobilized on carriers in a manner shown in schematic FIG.()-(), as well as antibody affinity separation matrices obtained by immobilizing such a protein ligand on a water-insoluble carrier. The affinity separation matrices are characterized by their excellent binding capacity and binding efficiency to a target molecule.


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