The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Nov. 12, 2016
Applicants:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Calitor Sciences, Llc, Newbury Park, CA (US);

Inventors:

Ning Xi, Newbury Park, CA (US);

Mingming Sun, Guangdong, CN;

Assignees:

Calitor Sciences, LLC, Newbury Park, CA (US);

Sunshine Lake Pharma Co., LTD., Dongguan, Guangdong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07C 309/30 (2006.01); A61K 31/4709 (2006.01); A61K 9/00 (2006.01); A61K 9/48 (2006.01); A61K 38/21 (2006.01); A61K 31/436 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 9/0053 (2013.01); A61K 9/48 (2013.01); A61K 31/436 (2013.01); A61K 31/4709 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to a crystalline form of N-(3-fluoro-4-((7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl)oxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide p-toluenesulfonate, the process for preparing the crystalline form thereof, and the pharmaceutical compositions comprising the crystalline form thereof. This invention also relates to a method of using such a crystalline form and pharmaceutical compositions comprising the crystalline form thereof in the treatment of hyperproliferative diseases in mammals, especially in humans.


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