The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2018
Filed:
Feb. 06, 2015
Applicant:
Rutgers, the State University of New Jersey, New Brunswick, NJ (US);
Inventors:
Richard H. Ebright, New Brunswick, NJ (US);
Yon W. Ebright, New Brunswick, NJ (US);
Soma Mandal, New Brunswick, NJ (US);
Richard Wilde, New Brunswick, NJ (US);
Shengjian Li, New Brunswick, NJ (US);
Assignee:
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/88 (2006.01); A61K 31/167 (2006.01); A61K 31/341 (2006.01); A61K 31/4402 (2006.01); A61K 31/4409 (2006.01); C07D 213/75 (2006.01); C07D 213/81 (2006.01); C07D 213/82 (2006.01); C07D 215/38 (2006.01); C07D 215/40 (2006.01); C07D 217/22 (2006.01); C07D 317/66 (2006.01); C07D 319/18 (2006.01); C07D 231/56 (2006.01); C07D 333/38 (2006.01); C07D 333/66 (2006.01); C07D 235/06 (2006.01); C07D 401/12 (2006.01); C07D 237/30 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 241/04 (2006.01); C07D 249/06 (2006.01); C07D 249/08 (2006.01); C07D 249/18 (2006.01); C07D 471/04 (2006.01); C07D 257/04 (2006.01); C07D 487/04 (2006.01); C07D 265/30 (2006.01); C07D 207/14 (2006.01); C07D 277/62 (2006.01); C07D 209/40 (2006.01); C07D 209/42 (2006.01); C07D 211/58 (2006.01); C07D 295/135 (2006.01); C07D 295/155 (2006.01); C07D 295/185 (2006.01); C07D 295/205 (2006.01); C07D 307/82 (2006.01); C07C 237/20 (2006.01); A01N 37/22 (2006.01); A01N 43/10 (2006.01); A01N 43/30 (2006.01); A01N 43/32 (2006.01); A01N 43/36 (2006.01); A01N 43/40 (2006.01); A01N 43/50 (2006.01); A01N 43/52 (2006.01); A01N 43/56 (2006.01); A01N 43/60 (2006.01); A01N 43/62 (2006.01); A01N 43/647 (2006.01); A01N 43/78 (2006.01); A01N 43/90 (2006.01); A01N 37/24 (2006.01); A01N 43/38 (2006.01); A01N 43/48 (2006.01); A01N 43/653 (2006.01); A01N 43/713 (2006.01); A01N 43/84 (2006.01); C07D 209/08 (2006.01); C07D 333/54 (2006.01);
U.S. Cl.
CPC ...
C07C 233/88 (2013.01); A01N 37/22 (2013.01); A01N 37/24 (2013.01); A01N 43/10 (2013.01); A01N 43/30 (2013.01); A01N 43/32 (2013.01); A01N 43/36 (2013.01); A01N 43/38 (2013.01); A01N 43/40 (2013.01); A01N 43/48 (2013.01); A01N 43/50 (2013.01); A01N 43/52 (2013.01); A01N 43/56 (2013.01); A01N 43/60 (2013.01); A01N 43/62 (2013.01); A01N 43/647 (2013.01); A01N 43/653 (2013.01); A01N 43/713 (2013.01); A01N 43/78 (2013.01); A01N 43/84 (2013.01); A01N 43/90 (2013.01); A61K 31/167 (2013.01); A61K 31/341 (2013.01); A61K 31/4402 (2013.01); A61K 31/4409 (2013.01); C07C 237/20 (2013.01); C07D 207/14 (2013.01); C07D 209/08 (2013.01); C07D 209/40 (2013.01); C07D 209/42 (2013.01); C07D 211/58 (2013.01); C07D 213/75 (2013.01); C07D 213/81 (2013.01); C07D 213/82 (2013.01); C07D 215/38 (2013.01); C07D 215/40 (2013.01); C07D 217/22 (2013.01); C07D 231/56 (2013.01); C07D 235/06 (2013.01); C07D 237/30 (2013.01); C07D 241/04 (2013.01); C07D 249/06 (2013.01); C07D 249/08 (2013.01); C07D 249/18 (2013.01); C07D 257/04 (2013.01); C07D 265/30 (2013.01); C07D 277/62 (2013.01); C07D 295/135 (2013.01); C07D 295/155 (2013.01); C07D 295/185 (2013.01); C07D 295/205 (2013.01); C07D 307/82 (2013.01); C07D 317/66 (2013.01); C07D 319/18 (2013.01); C07D 333/38 (2013.01); C07D 333/54 (2013.01); C07D 333/66 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05);
Abstract
The invention provides compounds having activity as bacterial RNA polymerase inhibitors and antibacterial agents, as well as compositions comprising the compounds and methods for their use. Specifically, phenylalanineamide and tyrosinamide compounds are disclosed that have inhibitory activity towardRNA polymerase. Use of these compounds in the treatment or prevention ofinfections in a mammal, is disclosed.
Ebright, Richard. (2018). Antibacterial agents: nα-aroyl-n-aryl-phenylalaninamides (U.S. Patent No. 9919998). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9919998
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile