The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2018

Filed:

Mar. 14, 2014
Applicants:

Sidney Hecht, Phoenix, AZ (US);

Rakesh Paul, Baltimore, MD (US);

Chenhong Tang, Tempe, AZ (US);

Manikandadas Mathilakathu Madathil, Tempe, AZ (US);

Chandrabali Bhattacharya, Tempe, AZ (US);

Inventors:

Sidney Hecht, Phoenix, AZ (US);

Rakesh Paul, Baltimore, MD (US);

Chenhong Tang, Tempe, AZ (US);

Manikandadas Mathilakathu Madathil, Tempe, AZ (US);

Chandrabali Bhattacharya, Tempe, AZ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 31/519 (2006.01); A61K 47/48 (2006.01); A61K 31/7042 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48092 (2013.01); A61K 31/4745 (2013.01); A61K 31/519 (2013.01); A61K 31/7042 (2013.01);
Abstract

The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using them are also provided.


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