The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2018
Filed:
Jul. 14, 2015
Applicant:
The United States of America, As Represented BY the Secretary of the Army, Washington, DC (US);
Inventor:
Sheetij Dutta, Silver Spring, MD (US);
Assignee:
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY, Washington, DC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/002 (2006.01); A61K 39/015 (2006.01); C07K 14/445 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); C07K 14/445 (2013.01); A61K 2039/55566 (2013.01);
Abstract
The present invention provides novel nucleotide sequence and other constructs used for expression of novel recombinantcircumsporozoite proteins in bacterial cells such as. Processes are provided for producing a soluble recombinantCSP from. Methods to produce a human-grade, highly immunogenic anti-malaria vaccine based on CSP are shown. The novel recombinantcircumsporozoite protein by itself or in combination with other malaria antigens or adjuvants can form the basis of an effective malaria vaccine.