The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2018
Filed:
Jan. 29, 2015
Applicant:
Johnson Matthey Public Limited Company, London, GB;
Inventors:
Saroop Matharu, Shirley, MA (US);
Brian Heinrich, Fitchburg, MA (US);
Aniruddh Singh, Acton, MA (US);
Mahmoud Mirmehrabi, Halifax, CA;
Assignee:
Johnson Matthey Public Limited Company, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); C07D 489/08 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 47/10 (2013.01); C07D 489/08 (2013.01);
Abstract
An improved method for the preparation of the low ABUK oxymorphone hydrochloride is provided. The oxymorphone hydrochloride is produced by hydrogenating a starting material comprising oxymorphone base and 14-hydroxymorphinone in a mixture comprising an alcohol, water and an acid, removing some of the water and adding more alcohol to the mixture.