The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2018
Filed:
Apr. 08, 2016
Applicant:
Bioresponse, L.l.c., Boulder, CO (US);
Inventors:
Michael A. Zeligs, Boulder, CO (US);
Irwin C. Jacobs, Defiance, MO (US);
Assignee:
BIORESPONSE, L.L.C., Boulder, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/404 (2006.01); A61K 47/00 (2006.01); A61K 47/06 (2006.01); A61K 9/08 (2006.01); A61K 9/10 (2006.01); A61K 31/122 (2006.01); A61K 31/138 (2006.01); A61K 31/23 (2006.01); A61K 31/275 (2006.01); A61K 31/357 (2006.01); A61K 31/4045 (2006.01); A61K 31/59 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/48 (2006.01); A61K 31/215 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/38 (2006.01); A61K 47/46 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 9/0014 (2013.01); A61K 9/0053 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 9/14 (2013.01); A61K 9/48 (2013.01); A61K 31/122 (2013.01); A61K 31/138 (2013.01); A61K 31/215 (2013.01); A61K 31/23 (2013.01); A61K 31/275 (2013.01); A61K 31/357 (2013.01); A61K 31/4045 (2013.01); A61K 31/59 (2013.01); A61K 47/00 (2013.01); A61K 47/06 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01); A61K 47/46 (2013.01);
Abstract
Disclosed herein are self-emulsifying compositions and formulations of Diindolylmethane ('DIM') and certain derivatives of DIM, their uses and methods of making. In particular, the disclosed compositions comprise a DIM-related indole as an active agent and a carrier, wherein the carrier comprises a solvent, one or more surfactants with an HLB of greater than 7, and one or more co-surfactants with an HLB equal to or less than 7. In certain aspects of the invention, the compositions disclosed herein show improved bioavailability.