The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2018
Filed:
Aug. 05, 2015
Applicants:
The Scripps Research Institute, LaJolla, CA (US);
Board of Regents of the University of Texas System, Austin, Austin, TX (US);
Inventors:
Dale Boger, LaJolla, CA (US);
Bruce Beutler, Irving, CA (US);
Assignees:
The Board of Regents of the University of Texas System, Austin, TX (US);
The Scripps Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/79 (2006.01); C07D 333/50 (2006.01); A61K 31/343 (2006.01); A61K 31/167 (2006.01); A61K 31/381 (2006.01); A61K 31/404 (2006.01); A61K 31/4439 (2006.01); C07D 307/85 (2006.01); A61K 39/39 (2006.01); C07D 209/42 (2006.01); C07D 405/12 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); A61K 31/498 (2006.01); C07D 403/12 (2006.01); A61K 31/506 (2006.01); C07C 237/44 (2006.01);
U.S. Cl.
CPC ...
A61K 31/343 (2013.01); A61K 31/167 (2013.01); A61K 31/381 (2013.01); A61K 31/404 (2013.01); A61K 31/4439 (2013.01); A61K 31/498 (2013.01); A61K 31/506 (2013.01); A61K 39/39 (2013.01); C07C 237/44 (2013.01); C07D 209/42 (2013.01); C07D 307/85 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07C 2601/14 (2017.05);
Abstract
A TLR-independent adjuvant compound that corresponds in structure to Formula I, below, or its pharmaceutically acceptable salt is disclosed in which X, Y, Z, n, R, R, R, Rand W are defined within. Also disclosed are a method of its preparation and use, as well as a pharmaceutical composition containing the same.