The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
Jun. 01, 2016
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Xingde Li, Ellicott City, MD (US);
Yicong Wu, North Potomac, MD (US);
Wenxuan Liang, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G02B 23/26 (2006.01); G02B 23/24 (2006.01); G01N 21/64 (2006.01); G01N 33/483 (2006.01); G02B 21/00 (2006.01); G02B 26/10 (2006.01); A61B 5/00 (2006.01); G01N 21/63 (2006.01); G02B 3/00 (2006.01); A61B 1/00 (2006.01);
U.S. Cl.
CPC ...
G02B 23/26 (2013.01); A61B 5/0068 (2013.01); A61B 5/0084 (2013.01); G01N 21/636 (2013.01); G01N 21/6458 (2013.01); G01N 33/4833 (2013.01); G02B 21/0008 (2013.01); G02B 23/243 (2013.01); G02B 23/2469 (2013.01); G02B 26/103 (2013.01); A61B 1/0017 (2013.01); G01N 2021/6478 (2013.01); G01N 2021/6484 (2013.01); G01N 2201/0866 (2013.01); G01N 2201/10 (2013.01); G02B 3/0087 (2013.01);
Abstract
The present invention is directed to a fiber optic device that enables multiphoton imaging with improved signal-to-noise ratio having a single piece of double-clad fiber (DCF). The device also includes all components for focusing, scanning and signal collection within an endomicroscope probe of 2.1 mm outer diameter (OD). The unprecedented imaging capability of this miniature endomicroscope is demonstrated herein via both ex vivo and in vivo experiments.