The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Aug. 31, 2012
Applicants:

Nikolai Vladimirovich Bovin, Moscow, RU;

Stephen Michael Henry, Auckland, NZ;

Igor Leonidovich Rodionov, Moscow Region, RU;

Inventors:

Nikolai Vladimirovich Bovin, Moscow, RU;

Stephen Michael Henry, Auckland, NZ;

Igor Leonidovich Rodionov, Moscow Region, RU;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/555 (2006.01); G01N 33/554 (2006.01); G01N 33/68 (2006.01); G01N 33/92 (2006.01); G01N 33/571 (2006.01);
U.S. Cl.
CPC ...
G01N 33/555 (2013.01); G01N 33/554 (2013.01); G01N 33/571 (2013.01); G01N 33/6815 (2013.01); G01N 33/92 (2013.01); G01N 2333/005 (2013.01); G01N 2333/20 (2013.01);
Abstract

Method of localizing a sulfhydryl (—SH) group containing biomolecule to the surface of a cell membrane by mixing in a volatile reaction buffer a molar excess of the sulfhydryl (—SH) group containing biomolecule with a lipid conjugated maleimide of the structure F-S-L as defined in the specification to provide a reaction mix, incubating the reaction mix for a time and at a temperature sufficient to allow all the lipid conjugated maleimide to have reacted with the sulfhydryl (—SH) group, and freeze-drying the reaction mix to remove the volatile reaction buffer and provide a reaction product. An aqueous solution of the reaction product is contacted with the cell membrane.


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Bovin, Nikolai. (2018). Facile laboratory method for localising biomolecules to the surface of cells and viruses (U.S. Patent No. 9915653). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9915653

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