The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
May. 27, 2016
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Christine E. Brown, Duarte, CA (US);
Stephen J. Forman, Duarte, CA (US);
Assignee:
City of Hope, Duarte, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); C07K 14/54 (2006.01); C07K 14/715 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C07K 14/73 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 35/17 (2013.01); C07K 14/5437 (2013.01); C07K 14/7051 (2013.01); C07K 14/70514 (2013.01); C07K 14/70578 (2013.01); C07K 14/7155 (2013.01); A61K 38/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01); C07K 2319/75 (2013.01); C12N 2510/00 (2013.01); C12N 2740/16043 (2013.01);
Abstract
Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13Rα2 (IL13Rα2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.