The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Jun. 16, 2015
Applicant:

Delenex Therapeutics Ag, Schlieren, CH;

Inventors:

Annemarie Honegger, Zürich, CH;

Titus Kretzschmar, Steinhausen, CH;

Simone Schmitt, Schlieren, CH;

Abdijapar Shamshiev, Zürich, CH;

Stefanie Grabulovski, Zürich, CH;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/24 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/245 (2013.01); G01N 33/6869 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/41 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/94 (2013.01); G01N 2333/545 (2013.01);
Abstract

The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.


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