The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Feb. 06, 2015
Applicant:

Inhibrx Llc, La Jolla, CA (US);

Inventors:

John C. Timmer, La Jolla, CA (US);

Brendan P. Eckelman, La Jolla, CA (US);

Grant B. Guenther, La Jolla, CA (US);

Peter L. Nguy, La Jolla, CA (US);

Henry Chan, La Jolla, CA (US);

Quinn Deveraux, La Jolla, CA (US);

Assignee:

Inhibrx LP, La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 14/81 (2006.01); C07K 16/24 (2006.01); C07K 14/715 (2006.01); C07K 14/765 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/811 (2013.01); C07K 14/7151 (2013.01); C07K 14/7155 (2013.01); C07K 14/765 (2013.01); C07K 14/8121 (2013.01); C07K 14/8125 (2013.01); C07K 16/241 (2013.01); A61K 38/00 (2013.01); C07K 2317/522 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01); C07K 2317/56 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C07K 2319/70 (2013.01);
Abstract

This invention relates to fusion proteins that include a whey acidic protein (WAP) domain-containing polypeptide and a second polypeptide. Additionally, the invention relates to fusion proteins that include a WAP domain-containing polypeptide a second polypeptide, and a third polypeptide. The second and/or third polypeptides of the fusion proteins of the invention are a Fe polypeptide; an albumin polypeptide; a cytokine targeting polypeptide; or a serpin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.


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