The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Dec. 07, 2009
Applicants:

Jean-paul Castaigne, Mont-Royal, CA;

Michel Demeule, Beaconsfield, CA;

Christian Che, Montréal, CA;

Carine Thiot, Montréal, CA;

Catherine Gagnon, Montréal-Nord, CA;

Inventors:

Jean-Paul Castaigne, Mont-Royal, CA;

Michel Demeule, Beaconsfield, CA;

Christian Che, Montréal, CA;

Carine Thiot, Montréal, CA;

Catherine Gagnon, Montréal-Nord, CA;

Assignee:

Angiochem Inc., Montreal, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/00 (2006.01); C07K 7/08 (2006.01); A61K 47/48 (2006.01); C07K 14/81 (2006.01);
U.S. Cl.
CPC ...
C07K 7/083 (2013.01); A61K 47/48246 (2013.01); C07K 14/8117 (2013.01); A61K 38/00 (2013.01); C07K 2319/03 (2013.01);
Abstract

The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a peptide therapeutic selected from the group consisting of neurotensin, a neurotensin analog, or a neurotensin receptor agonist. The compounds of the invention can be used to treat any disease in which increased neurotensin activity is useful and can be used to induce hypothermia or analgesia.


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