The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9914696 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 13, 2018

Filed:

Mar. 09, 2015
Applicant:

Repros Therapeutics Inc., The Woodlands, TX (US);

Inventors:

Joseph S. Podolski, The Woodlands, TX (US);

Kuang Hsu, The Woodlands, TX (US);

Assignee:

Repros Therapeutics Inc., The Woodlands, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 213/08 (2006.01); C07C 213/10 (2006.01); C07C 59/265 (2006.01); C07C 51/41 (2006.01);
U.S. Cl.
CPC ...
C07C 213/08 (2013.01); C07C 51/412 (2013.01); C07C 59/265 (2013.01); C07C 213/10 (2013.01); C07B 2200/09 (2013.01);
Abstract

The present invention provides a one-pot method for synthesizing clomiphene (a mixture of the isomers cis-clomiphene and trans-clomiphene) utilizing a single solvent. In a preferred embodiment, the single solvent is dichloromethane (DCM, also known as methylene chloride). The present invention provides an improved method for synthesizing clomiphene and purifying clomiphene isomers.


Find Patent Forward Citations

Podolski, Joseph. (2018). Clomiphene synthesis using a single solvent (U.S. Patent No. 9914696). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9914696

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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