The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
May. 25, 2016
Applicant:
Horizon Therapeutics, Llc, Lake Forest, IL (US);
Inventors:
Huai-Chueh Chang, Tower Lakes, IL (US);
Steven S. Pfeiffer, Camarillo, CA (US);
Vasilios H. Iskos, Chicago, IL (US);
Maki Uragami, Bethlehem, PA (US);
Steven Weissman, Short Hills, NJ (US);
Andrew Thompson, Mountainside, NJ (US);
Assignee:
Horizon Therapeutics, LLC, Lake Forest, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/235 (2006.01); C07C 69/616 (2006.01); C07C 51/29 (2006.01); C07C 57/30 (2006.01); C07C 67/14 (2006.01);
U.S. Cl.
CPC ...
C07C 69/616 (2013.01); C07C 51/29 (2013.01); C07C 57/30 (2013.01); C07C 67/14 (2013.01);
Abstract
Provided is a process for preparing 4-phenyl-1-butyric acid, comprising: reacting 4-phenyl-1-butanol with sodium chlorite, a nitroxyl radical catalyst and sodium hypochlorite in an organic solvent and a phosphate buffer; and quenching the reaction with sodium sulfite to produce 4-phenyl-1-butyric. Also provided is 4-phenyl-1-butyric acid prepared by such a process.