The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Oct. 26, 2011
Applicants:

Dirk Wybe Grijpma, Hengelo, NL;

Rudolf Robert Maria Bos, Groningen, NL;

Anne Cornelis Van Leeuwen, Groningen, NL;

Inventors:

Dirk Wybe Grijpma, Hengelo, NL;

Rudolf Robert Maria Bos, Groningen, NL;

Anne Cornelis Van Leeuwen, Groningen, NL;

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/46 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61L 27/18 (2006.01); A61L 24/00 (2006.01); A61L 27/42 (2006.01); A61L 31/12 (2006.01);
U.S. Cl.
CPC ...
A61L 27/46 (2013.01); A61L 24/0063 (2013.01); A61L 27/18 (2013.01); A61L 27/425 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 31/123 (2013.01); A61L 2300/112 (2013.01); A61L 2300/412 (2013.01); A61L 2300/60 (2013.01); A61L 2430/02 (2013.01);
Abstract

The present invention relates to methods for providing polymeric composites with bone forming, such as with osteogenic and/or osteoinductive and/or osteoconductive, properties. The present invention further relates to polymeric composites provided by the present method and the use of thereof for bone implants, or grafts, specifically the use thereof for orbital floor reconstruction. Specifically, the present invention relates to methods for providing a composite with bone forming properties, the method comprises the steps of: a) providing a liquid, or liquefied, polymeric composition of homopolymers or copolymers of 1,3-trimethylene carbonate (TMC); b) adding to said liquid, or liquefied, polymeric composition one or more agents with osteogenic and/or osteoinductive and/or osteoconductive properties thereby providing a dispersion of said agents in said liquid or liquefied polymeric composition; and c) crosslinking the product obtained, thereby providing a composite with bone forming properties.


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