The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
Aug. 06, 2015
Applicants:
Vib Vzw, Gent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Inventors:
Kiavash Movahedi, Frankfurt am Main, DE;
Damya Laoui, Limal, BE;
Steve Schoonooghe, Kessel-Lo, BE;
Geert Raes, Sint-Genesius-Rode, BE;
Patrick De Baetselier, Berchem, BE;
Jo Van Ginderachter, Ninove, BE;
Nick Devoogdt, Zemst, BE;
Tony Lahoutte, Ganshoren, BE;
Assignees:
VIB VZW, Gent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/10 (2006.01); C07K 16/28 (2006.01); A61K 49/00 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 51/1027 (2013.01); A61K 47/48484 (2013.01); A61K 47/48561 (2013.01); A61K 47/48761 (2013.01); A61K 49/0002 (2013.01); B82Y 5/00 (2013.01); C07K 16/2851 (2013.01); C07K 2317/22 (2013.01); C07K 2317/35 (2013.01);
Abstract
The disclosure relates to activities and characteristics of tumor-associated macrophages (TAMs). In particular, immunoglobulin single variable domains are provided against markers of TAMs, and methods using the same for in vivo imaging of tumor cells, as well as cancer diagnostics and therapeutics.