The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Jun. 10, 2014
Applicant:

Universitat Bayreuth, Bayreuth, DE;

Inventors:

Dirk Schüler, Neuried, DE;

Isabel Kolinko, Planegg, DE;

Assignee:

UNIVERSITAT BAYREUTH, Bayreuth, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12N 15/74 (2006.01); C12P 21/06 (2006.01); C12P 19/34 (2006.01); A61K 49/18 (2006.01); C07K 14/195 (2006.01); C12P 3/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1896 (2013.01); C07K 14/195 (2013.01); C12N 15/74 (2013.01); C12P 3/00 (2013.01);
Abstract

Recombinant host cells are provided. The cell genome contains heterologous gene expression cassettes capable of being expressed in the host cell, where the gene expression cassettes encode a nucleic acid sequence encompassing at least 80% of the full-length sequence of the mamAB operon, the mamGDFC operon, and the tmms6 operon of a magnetotactic alphaproteobacterium, respectively. The cells may further comprise gene expression cassettes capable of being expressed in the host cell, where the gene expression cassettes encode a nucleic acid sequence encompassing at least 80% of the full-length sequence of the mamXY operon and/or the feoABI operon of a magnetotactic alphaproteobacterium; where the recombinant host cell, upon expression of the gene expression cassettes in their entirety, is capable of producing magnetic nanoparticles. Preferably, the recombinant host cell is derived from. Methods of producing these recombinant host cells by genetic transposition are provided.


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