The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Aug. 20, 2015
Applicant:

Professional Compounding Centers of America (Pcca), Houston, TX (US);

Inventors:

Chris V. Simmons, Sugar Land, TX (US);

Daniel Banov, Sugar Land, TX (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 47/44 (2017.01); A61K 47/24 (2006.01); A61K 9/00 (2006.01); A61K 47/12 (2006.01); A61K 36/889 (2006.01); A61K 36/47 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/0014 (2013.01); A61K 9/0046 (2013.01); A61K 36/47 (2013.01); A61K 36/889 (2013.01); A61K 47/12 (2013.01); A61K 47/24 (2013.01); A61K 47/44 (2013.01);
Abstract

The present disclosure refers to transdermal pharmaceutical bases that include a synergistic combination of a silicone base with a natural permeation enhancement composition (NPE). Further, these transdermal pharmaceutical bases are proposed to treat ear diseases in mammals. The silicone base includes silicone, pracaxi oil, and seje oil. Additionally, the NPE composition includes one or more phospholipids, one or more oils rich in essential fatty acids, behenic acid, and oleic acid, one or more skin lipids, and one or more butters rich in linoleic acid and linolenic acid. The synergistic combination of aforementioned natural components exhibit enhanced healing properties, thereby providing organic acids with antioxidant, antibacterial, and antifungal properties. The transdermal pharmaceutical bases are employed to increase the residence time of the medicament in the ear canal, and increase the penetration of the APIs into the affected area, thereby enhancing treatment effectiveness.


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