The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
Dec. 03, 2013
Applicant:
Merrimack Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Victor Moyo, Ringoes, NJ (US);
Bart S. Hendriks, Belmont, MA (US);
Thomas Wickham, Groton, MA (US);
Elena Geretti, Cambridge, MA (US);
Joseph G. Reynolds, North Andover, MA (US);
Christopher W. Espelin, Belmont, MA (US);
Assignee:
Merrimack Pharmaceuticals, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/127 (2006.01); A61K 31/704 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); C07K 16/32 (2006.01); A61J 1/16 (2006.01); A61K 9/00 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61J 1/16 (2013.01); A61K 9/0019 (2013.01); A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 31/704 (2013.01); A61K 47/6871 (2017.08); A61K 47/6913 (2017.08); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 16/40 (2013.01); A61K 2039/507 (2013.01); C07K 2317/76 (2013.01);
Abstract
Methods for treating cancer patients with HER2-positive tumors are disclosed. The methods comprise administering to a patient a therapeutically effective amount of a combination of (i) an anthracycline-loaded immunoliposome with a targeting moiety that is a first anti-HER2 antibody and (ii) an anti-cancer therapeutic comprising a second anti-HER2 antibody.