The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2018
Filed:
Mar. 13, 2015
Applicant:
Shimojani, Llc, San Francisco, CA (US);
Inventors:
Lawrence M. Kauvar, San Francisco, CA (US);
Damir Janigro, Cleveland Heights, OH (US);
Assignee:
Shimojani, LLC, San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/49 (2006.01); A61K 38/48 (2006.01); G01N 33/68 (2006.01); C07K 16/22 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 38/482 (2013.01); A61K 38/49 (2013.01); C07K 16/22 (2013.01); C12Y 304/21068 (2013.01); C12Y 304/21073 (2013.01); C12Y 304/24029 (2013.01); G01N 33/6893 (2013.01); G01N 2333/4727 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/52 (2013.01);
Abstract
Identification of candidates for treatment and treatment of subjects experiencing cerebral ischemia wherein the treatment employs a thrombolytic or thrombectomy agent and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are determined by testing the blood of a patient for total S-100B or for S-100BB as a marker of blood brain barrier integrity.