The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Jan. 12, 2016
Applicant:

Uvic Industry Partnerships Inc., Victoria, CA;

Inventors:

Caroline E. Cameron, Victoria, CA;

Rebecca M. Hof, Victoria, CA;

Simon A. Houston, Victoria, CA;

Martin John Boulanger, Victoria, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); C07K 14/20 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0225 (2013.01); C07K 14/20 (2013.01); A61K 38/00 (2013.01); A61K 2039/57 (2013.01); A61K 2039/575 (2013.01);
Abstract

The present application provides methods of stimulating an immune response, such as a protective immune response againstinfection. Such methods utilize fragments of the Tp0751 protein (such as any of SEQ ID NOs: 3-10, those N-terminally truncated from amino acids 1 through 77, 1 through 114, or anywhere in between, e.g., those that start at any amino acid from 78 to 115). In some examples, a Tp0751 protein fragment has a mutated HEXXH site (HEXXH is the wild-type sequence). Also provided are the isolated soluble Tp0751 protein fragments that include a wild-type or mutated HEXXH site, as well as nucleic acids encoding such proteins and kits that include such proteins.


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