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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9913835 B1

PDFFull Text
Date of Patent:
Mar. 13, 2018

Filed:

Mar. 02, 2017

Methods for controlled proliferation of stem cells / generating inner ear hair cells using n-(alkylcarbamoyl)-1h-pyrazol-4-yl)-nicotinamide based compounds

Applicant:

Frequency Therapeutics, Inc., Woburn, MA (US);

Inventors:

Christopher Loose, Winchester, MA (US);

Will McLean, North Haven, CT (US);

Melissa Hill-Drzewi, Durham, CT (US);

Assignee:

Frequency Therapeutics, Inc., Woburn, MA (US);

Attorneys:

Cooley LLP

J. Dean Farmer

Xixi Sun

Primary Examiner:

Kristin Vajda

Int. Cl.
CPC ...
A61K 31/455 (2006.01);
U.S. Cl.
CPC ...
A61K 31/455 (2013.01);
Abstract

The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a N-(1H-pyrazol-4-yl)-nicotinamide moiety having a Formula I: and pharmaceutically acceptable salts thereof.

Find Patent Forward Citations

Loose, Christopher. (2018). Methods for controlled proliferation of stem cells / generating inner ear hair cells using n-(alkylcarbamoyl)-1h-pyrazol-4-yl)-nicotinamide based compounds (U.S. Patent No. 9913835). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9913835

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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