The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2018

Filed:

Jun. 20, 2016
Applicant:

Macau University of Science and Technology, Taipa, MO;

Inventors:

Liang Liu, Taipa, MO;

Lai Han Leung, Taipa, MO;

Xia Li, Taipa, MO;

Xing-Xing Fan, Taipa, MO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/122 (2006.01);
U.S. Cl.
CPC ...
A61K 31/122 (2013.01);
Abstract

A compound suitable for treating EGFR-dependent non-small cell lung cancer exceptionally inhibits activity of the EGFR kinase, in particular in EGFR-dependent non-small cell lung cancer with intrinsic or acquired resistance against at least one EGFR inhibitor. Methods for inhibiting EGFR kinase activity in non-small cell lung cancer cells which harbor an abnormality in the EGFR gene and for targeting cancer cells harboring an abnormality in EGFR gene by contacting EGFR-dependent non-small cell lung cancer cells with said compound are also provided. The compounds allow for an advantageous inhibition of the EGFR kinase activity and induction of apoptosis of the non-small cell lung cancer cells with abnormality in the EGFR gene. Hence, said compounds represent a highly promising treatment option for patients harboring EGFR-dependent cancer.


Find Patent Forward Citations

Liu, Liang. (2018). Hydroxynaphthoquinone compounds for treatment of non-small cell lung cancer (U.S. Patent No. 9913811). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9913811

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