The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2018
Filed:
Aug. 08, 2014
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Daniel Beacham, Eugene, OR (US);
Jeffrey Dzubay, Eugene, OR (US);
Kyle Gee, Springfield, OR (US);
Vladimir Martin, Eugene, OR (US);
Aleksey Rukavishnikov, Eugene, OR (US);
Assignee:
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/84 (2006.01); C07K 1/13 (2006.01); C09B 7/00 (2006.01); C09B 11/12 (2006.01); C09B 11/28 (2006.01); C09B 57/00 (2006.01); C09B 69/00 (2006.01); G01N 31/22 (2006.01); C09B 11/24 (2006.01); G01N 33/50 (2006.01); G01N 33/58 (2006.01); G01N 33/80 (2006.01); C07D 311/82 (2006.01); C07D 311/90 (2006.01); C07D 405/12 (2006.01); C07D 413/04 (2006.01); C07D 491/22 (2006.01); C07D 209/14 (2006.01); C09K 11/06 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
G01N 33/84 (2013.01); C07D 209/14 (2013.01); C07D 311/82 (2013.01); C07D 311/90 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01); C07D 491/22 (2013.01); C07F 5/02 (2013.01); C07K 1/13 (2013.01); C09B 7/00 (2013.01); C09B 11/12 (2013.01); C09B 11/24 (2013.01); C09B 11/28 (2013.01); C09B 57/00 (2013.01); C09B 69/00 (2013.01); C09K 11/06 (2013.01); G01N 31/22 (2013.01); G01N 33/5005 (2013.01); G01N 33/5091 (2013.01); G01N 33/582 (2013.01); G01N 33/80 (2013.01); G01N 2333/245 (2013.01); Y10T 436/143333 (2015.01);
Abstract
A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: